Cellectric, Resistell and Lausanne University Hospital will collaborate on a joint Eurostars project to build Phenotech-CF, a workflow that will reshape how antimicrobials are delivered to patients suffering from cystic fibrosis.
In total, the project has been awarded nearly €2.7 million, and is projected to last three years.
Muttenz and Lausanne, Switzerland, Vienna, Austria – March 4, 2024 –
Cellectric and Resistell are delighted to announce the launch of a collaborative project which will see the two develop a workflow capable of accelerating the pace at which cystic fibrosis patients receive targeted antibiotic treatments.
The two companies will combine Cellectric’s proprietary sample purification and preparation technology with Resistell’s innovative nanomotion-based antimicrobial susceptibility testing platform to form Phenotech-CF, one complete operational workflow.
Phenotech-CF will begin development on April 1st; a process that is projected to take two years. Afterwards, researchers at Lausanne University Hospital (CHUV) and University of Lausanne (UNIL) will subject it to a full year of validation testing.
The joint effort has been awarded funding from Eurostars, an initiative of the Horizon program that financially supports projects between small and medium enterprises.
In total, the three-year project will receive nearly €2.7 million in backing. Resistell will receive €1.54 million and Cellectric, €830,000. The remainder will go to CHUV.
Beyond helping those with cystic fibrosis, Phenotech-CF will serve as a valuable tool in the fight against antimicrobial resistance, an issue the World Health Organization claims contributed to nearly 5m deaths worldwide in 2019, and one that is only set to get worse without intervention.
Phenotech-CF will also be used to help patients suffering from other types of infection and, going forward, could be used to test new antimicrobial agents, including phages.
“We are incredibly excited to partner with Resistell on this project and are hugely appreciative of Horizon Europe for its recognition. For too long, clinicians have lacked adequate insights about the nature of bacterial infections, leading to improper antibiotic use. As AMR becomes a global issue, it is vital that companies like ours act now to combat its spread.”
“Pharmaceutical companies are waking up to the fact that unless they act quickly, their current generation of antibiotics will soon stop working. By combining Resistell and Cellectric’s technologies, we will create a tool that will prolong their lifespan, while also creating a platform for the subsequent development and testing of new agents, a process that could save millions of lives.”
“We at CHUV are incredibly excited to serve as the hosts for this project. We believe that the combined workflow, Phenotech-CF, will not only help our clinicians in their day-to-day work, ensuring vulnerable cystic fibrosis patients are given the correct treatment, but also help in our search for new antimicrobial agents.”
For further information, please contact:
RHA Communications
barnaby@rhacomms.eu
Cellectric
office@cellectric.com
Resistell
contact@resistell.com
University Hospital Lausanne
gregory.resch@chuv.ch
Notes To Editors
About Cellectric
Founded in 2021 as a spin-off from the Austrian Institute of Technology, Cellectric has developed a new way of manipulating cell-containing media using state-of-the-art dielectric materials to induce highly targeted electrodynamic effects, allowing for selective permeabilization or destruction of specific target cells in a complex sample.
Cellectric is initially looking to apply its technology in sepsis and sepsis-adjacent indications, where its platform can be used to rapidly isolate and identify bacteria, hastening the pace at which diagnoses can be made. Beyond these initial showcase indications, the company plans to apply its platform to the isolation of leukocytes from human whole blood, from which a plethora of advanced therapy-related steps can be improved and simplified.
About Resistell
Resistell was founded as a spin-off from École Polytechnique Fédérale de Lausanne (EPFL) in 2018 with the goal of preventing the development of antimicrobial resistance. It hopes to do this by enabling clinicians to deliver targeted antibiotic therapies as quickly as possible.
The company’s Antibiotic Susceptibility Testing (AST) platform measures vibrations produced by living bacterial cells. Because this approach is growth-independent, it can be performed rapidly, reducing the time-to-result from days to just hours. Moreover, Resistell’s technology can indicate which antibiotic will be most effective in treating given infection.
About Eurostars
Eurostars is a European subsidy program that funds and supports innovative partnerships between small and medium enterprises. The funding comes from the Horizon Europe program and is available to innovators looking to work with universities and research centres in 37 participating countries.
Since 2014, almost €2 billion has been given out by Eurostars. A 2017 analysis of completed Eurostars projects found that nearly 90% delivered on their intended goals and that companies who successfully completed their projects saw their revenues grow 18%.
